Nobel Centennial Symposia

Frontiers of Molecular Science

December 4-7, 2001 Friiberghs Manor, Örsundsbro and Stockholm University

December 4

Introduction

Bengt Nordén (Chalmers University of Technology) Overview and Scientific Appetizers

I. Fundamentals

Ahmed H. Zewail (California Institute of Technology) Dynamical Chemistry and Biology: From Fundamentals to Complexity

W. Moerner (Stanford University) Single-Molecule Spectroscopy: from Low Temperature Physical Chemistry to Biophysics

Richard N. Zare (Stanford University) Prospects for Advances in Micro- and Nano-scale Chemical Analysis

Rudolph A. Marcus (California Institute of Technology) Unimolecular Reactions and the Strange Mass-Independent Isotope Effect in Chemistry

Barry Ninham (Australian National University) Flaws in the Fabric of Physical Chemistry

December 5

II. Biological Systems

John E. Walker (MRC, Cambridge) The Rotary Mechanism of ATP Synthase

George P. Smith (University of Missouri-Columbia) Selection Versus Design in Chemical Engineering

Arthur L. Horwich (Yale University) Chaperonin-assisted Polypeptide Folding

Roger Kornberg (Stanford University) Eukaryotic Gene Transcription at Atomic Resolution

Peter B. Dervan (California Institute of Technology) Regulation of Gene Expression by Synthetic DNA Binding Ligands

Stephan Krauss (Rikshospitalet, Oslo) Targeted Gene Conversion

Kurt Wüthrich (Institut für Molekularbiologie und Biophysik) Meeting Future Demands of Structural Biology and Structural Genomics with NMR

Tom Steitz (Yale University) Functional Insights from the Structure of the Large Ribosomal Subunit and its Complexes with Ligands

Aaron Klug (MRC, Cambridge) Zinc Finger Peptides for Regulation of Gene Expression

December 6

III. Synthesis

Jean-Marie Lehn (Université Louis Pasteur, Strasbourg) Steps Towards Complex Matter: Information, Self- organization and Adaptation in Molecular and Supramolecular Systems

K. Barry Sharpless Engaging Enzymes in the Synthesis of Their Own Inhibitors

IV. Structures and Interfaces

Peter G. Schultz Functional Molecules: A Lesson from Nature

J. Fraser Stoddart (University of California, Los Angeles) The Nature of the Mechanical Bond

Gerhard Ertl (Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin) Dynamics of Reactions at Solid Surfaces

Final Remarks

Bengt Nordén General Discussion

December 7

(Aula Magna, Frescati, Stockholm)

V. Chemistry in the New Century: "Molecules and Life"

Panel: Nordén, Zewail, Walker, Dervan, Corey, Whitesides (Open part of Nobel Centennial Symposium)

Press Conference

Participants
Per Ahlberg	Göteborg University
Mikael Akke	Lund University
Bo Albinsson	CTH, Göteborg
Peter Brzezinski	Stockholm University
Carl-Ivar Brändén	Karolinska Institutet
Jan-Erling Bäckvall	Stockholm University
Jan-Otto Carlsson	Uppsala University
Ann-Kristin Danielsson	The Royal Swedish Academy
Ylva Engström	Stockholm University
Sture Forsén	Lund University
Michael Freemantle	Chem. & Eng. News
Ingmar Grenthe	KTH, Stockholm
Salo Gronowitz	Lund University
Astrid Gräslund	Stockholm University
Peter Gölitz	Angewandte Chemie
Gunnar von Heijne	Stockholm University
Torleif Härd	KTH, Stockholm
Jan Kihlberg	Umeå University
Reiko Kuroda	University of Tokyo
Torvard Laurent	Uppsala University
Sven Lidin	Stockholm University
Anders Liljas	Lund University
Per Lincoln	Göteborg University
Göran Lindblom	Umeå University
Björn Lindman	Lund University
Ylva Lindqvist	Karolinska Institutet
Sara Linse	Lund University
Karin Markides	Uppsala University
Christina Moberg	KTH, Stockholm