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The Nobel Prize in Chemistry 2004
Aaron Ciechanover, Avram Hershko, Irwin Rose

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The Nobel Prize in Chemistry 2004 – Animation

 

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"Kiss of Death"
The proteins that are to be destructed are marked with a label - the molecule ubiquitin. Proteins so labelled are then rapidly broken down – degraded – in cellular "waste disposers" called proteasomes.

 

Dödsmärkning
De proteiner som ska förstöras förses med en "etikett", molekylen ubiquitin. De märkta proteinerna bryts sedan snabbt ner i cellulära "avfallskvarnar" som kallas proteasomer.

 

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