Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1947
Carl Cori, Gerty Cori, Bernardo Houssay

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Gerty Cori - Facts

Gerty Theresa Cori, née Radnitz

Gerty Theresa Cori, née Radnitz

Born: 15 August 1896, Prague, Austria-Hungary (now Czech Republic)

Died: 26 October 1957, St. Louis, MO, USA

Affiliation at the time of the award: Washington University, St. Louis, MO, USA

Prize motivation: "for their discovery of the course of the catalytic conversion of glycogen"

Field: biochemistry, metabolism, physiology

Prize share: 1/4

Discovered the Course of the Catalytic Conversion of Glycogen

Gerty and Carl Cori took an interest in how the body utilizes energy. In 1929, they described what is known as the Cori cycle; an important part of metabolism. Lactic acid forms when we use our muscles, which is then converted into glycogen in the liver. Glycogen, in turn, is converted into glucose, which is absorbed by muscle cells. The pair continued to investigate how glycogen is broken down into glucose and, in 1938-1939, were able to both identify the enzyme that initiates the decomposition and also to use the process to create glycogen in a test tube.

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