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Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1950
Edward C. Kendall, Tadeus Reichstein, Philip S. Hench

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Edward C. Kendall - Facts

Edward Calvin Kendall

Edward Calvin Kendall

Born: 8 March 1886, South Norwalk, CT, USA

Died: 4 May 1972, Princeton, NJ, USA

Affiliation at the time of the award: Mayo Clinic, Rochester, MN, USA

Prize motivation: "for their discoveries relating to the hormones of the adrenal cortex, their structure and biological effects"

Field: biochemistry, endocrinology

Prize share: 1/3

Work

Situated atop the kidneys are two small glands, the adrenal glands. Their function was unknown for a long time, but if they were injured, deficiency diseases ensued that ended in death. In the mid-1930s Edward Kendall and Tadeus Reichstein succeeded in isolating and analyzing the composition of a number of similar hormones derived from the adrenal cortex. These became the basis for cortisone preparations that, with input from Kendall and Philip Hench, were used at the end of the 1940s to treat rheumatoid arthritis and other inflammations.

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