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Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 2007

Two ideas come together

The process of gene targeting involves two steps.

Capecchi and Smithies discovered that homologous
recombination could be used to specifically modify
genes in mammalian cells.

Evans identified and isolated embryonic stem cells
(ES cells) from early mouse embryos (blastocysts).
He also showed that ES cells can be used as vehicles
to transmit genetic information in mice.

Genes altered in vitro can thus be passed on to future
generations.

Contents:
| The Nobel Prize in Physiology or Medicine 2007 | Two ideas come togheter | Gene targeting in ES cells | From gene targeted ES cells to gene targeted mice | Gene targeting - a versatile technology | Credits |
Nobel Poster from the Nobel Committee for Physiology or Medicine, web adapted by Nobel Web AB.


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