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 Towards an Understanding of Integrative Brain Functions. Analyses at Multiple Levels
(1997, NS 103)
June 4-7, Nobel Forum, Karolinska Institutet, Stockholm
Kjell Fuxe, Sten Grillner, Tomas Hökfelt, Lars Olson and Luigi F. Agnati
Proceedings: Towards an Understanding of Integrative Brain Functions, published in Brain Research Reviews, Journal Special Issue, vol 26, no 3 (1998) and hardbound (1998), Elsevier Science Ltd, Amsterdam.

ISBN 0-444-50097-9


More information about Nobel Symposium 103


Table of Contents (with links to abstracts)  
Preface vii
List of participants
I. Cortical maps and microcircuits
Emotion in the perspective of an integrated nervous system
A. R. Damasio (USA)
(No abstract available)
Structural divisions and functional fields in the human cerebral cortex 
P. E. Roland and K. Zilles (Sweden, Germany)
Functional magnetic resonance imaging of mental rotation and memory scanning: a multidimensional scaling analysis of brain activation patterns
G. A. Tagaris, W. Richter, S. -G. Kim, G. Pellizzer, P. Andersen, K. Ugurbil and A.P. Georgopoulous (USA)
(No abstract available)
Salient featrues of synaptic organisation in the cerebral cortex 
P. Somogyi, G. Tamás, R. Lujan and E. H. Buhl (UK, Hungary)
II. Wiring and volume transmission
The emergence of the volume transmission concept  
M. Zoli, C. Torri, R. Ferrai, A. Jansson, I. Zini, K. Fuxe and L. F. Agnati (Italy, Sweden)
Re-evaluation of the role of the dopamine transporter in dopamine system homeostasis 
R. R. Gainetdinov, S. R. Jones, F. Fumagalli, R. M. Wightman and M. G. Caron (USA)
Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system 
T. Hökfelt, C. Broberger, X. Zhang, M. Diez, J. Kopp, Z.-Q. Xu, M. Landry, L. Bao, M. Schalling, J. Koistinaho, S. J. DeArmond, S. Prusiner, J. Gong and J. H. Walsh (Sweden, People's Republic of China, Finland, USA)


Nitric oxide and carbon monoxide: parallel roles as neural messengers 
S. H. Snyder, S. R. Jaffrey and R. Zakhary (USA)
Gap junction wiring: a 'new' principle in cell-to-cell communication in the nervous system? 
R. Dermietzel (Germany)


Intrinsic function of a neuronal network - a vertebrate central pattern generator 
S. Grillner, Ö. Ekeberg, A. El Manira, A. Lansner, D. Parker, J. Tegnér and P. Wallén (Sweden)


III. Fast and slow receptors and their regulation
Brain nicotinic receptors: structure and regulation, role in learning and reinforcement 
J.-P. Changeux, D. Bertrand, J.-P. Corringer, S. Dehaene, S. Edelstein, C. Léna, N. Le Novère, L. Marubio, M. Picciotto and M. Zoli (France)


RNA editing of brain glutamate receptor channels: mechanism and physiology 
P. H. Seeburg, M. Higuchi and R. Sprengel (Germany)
Glutamate receptors: brain function and signal transduction 
S. Nakanishi, Y. Nakajima, M. Masu, Y. Ueda, K. Nakahara, D. Watanabe, S. Yamaguchi, S. Kawabata and M. Okada (Japan)
Functional implications of multiple dopamine receptor subtypes: D1/D3 receptor coexistence
J. -C. Schwartz, J. Diaz, R. Bordet, N. Griffon, S. Perachon, C. Pilon, S. Ridray and P. Sokoloff (France)
IV. Integration at the receptor level and beyond
Signal transduction molecules at the glutamatergic postsynaptic membrane 
M. B. Kennedy (USA)
Integrated events in central dopamine transmission as analyzed at multiple levels. Evidence for intramembrane adenosine A2A/dopamine D2 and adenosine A1/dopamine D1 receptor interactions in the basal ganglia
K. Fuxe, S. Ferré, M. Zoli and L. F. Agnati (Sweden, Italy)
The DARPP-32/protein phosphatase-1 cascade: a model for signal integration
P. Greengard, A. C. Nairn, J. -A. Girault, C. C. Ouimet, G. L. Snyder, G. Fisone, P. B. Allen, A. Fienberg and A. Nishi (USA, France, Sweden)

(No abstract available)
Role of reelin in the control of brain development
T. Curran and G. D'Arcangelo (USA)
V. Trophic and cytokine signalling
Neurotophin receptors: mediators of life and death
M. Chao, P. Casaccia-Bonnefil, B. Carter, A. Chittka, H. Kong and S. O. Yoon (USA)
On CNS repair and protection strategies: novel approaches with implications for spinal cord injury and Parkinson's disease 
L. Olson, H. Cheng, R. H. Zetterström, L. Solomin, L. Jansson, L. Giménez-Llort, B. J. Hoffer and T. Perlmann (Sweden, Taiwan, USA)
Interleukin-1 receptors: cloning studies and role in central nervous system disorders
S. A. Loddock, C. Liu, T. Takao, K. Hashimoto and E. B. De Souza (USA, Japan)
Inflammatory cytokines: putative regulators of neuronal and neuro-endocrine function 
J. Raber, O. Sorg, T. F. W. Horn, N. Yu, G. F. Koob, I. L. Campbell and F. E. Bloom (USA, Switzerland)
Transgenic mice and cytokine actions in the brain: bridging the gap between structural and functional neuropathology 
I. L. Campbell (USA)
VI. Cognition, memory and mind
Gene regulation of cell adhesion: a key step in neural morphogenesis 
G. M. Edelman and F. S. Jones (USA)
Long-term potentiation and spatial training are both associated with the generation of new excitatory synapses
P. Anderson and A. Figenschouch Soleng (Norway)
(No abstract available)
Positive and negative regulatory mechanisms that mediate long-term memory storage 
T. Abel and E. Kandel (USA)
How to study consciousness scientifically
J. R. Searle (USA)
(No abstract available)
Author Index 388


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