Video lectures from Nobel Laureates in Physiology or Medicine

The Nobel Laureates are required “to give a lecture on a subject connected with the work for which the prize has been awarded”according to the Nobel Foundation statutes. The lecture should be given before, or no later than six months after, the Nobel Prize Award Ceremony, which takes place in Stockholm or, in the case of the Peace Prize, in Oslo on 10 December.

Videos of Nobel Lectures in Physiology or Medicine


Nobel Lecture by Harvey J. Alter
Nobel Lecture by Michael Houghton
Nobel Lecture by Charles M. Rice


The von Hippel-Lindau Tumor Suppressor Protein: Insights into Oxygen Sensing
Nobel Lecture by William G. Kaelin Jr
Elucidation of Oxygen Sensing Systems in Human and Animal Cells
Nobel Lecture by Sir Peter J. Ratcliffe
Hypoxia-Inducible Factors in Physiology and Medicine
Nobel Lecture by Gregg L. Semenza


Immune Checkpoint Blockade in Cancer Therapy: New insights, opportunities, and prospects for cures
Nobel Lecture by James P. Allison
Serendipities of acquired immunity
Nobel Lecture by Tasuku Honjo


The Little Flies: Multifaceted Basic Research Coming Out Better than Intended
Nobel Lecture by Jeffrey C. Hall

The Circadian Clock, Transcriptional Feedback and the Regulation of Gene Expression
Nobel Lecture by Michael Rosbash

Time Travels: A 40 Year Journey from Drosophila’s Clock Mutants to Human Circadian Disorders
Nobel Lecture by Michael W. Young


Autophagy – an Intracellular Recycling System
Nobel Lecture by Yoshinori Ohsumi


Ivermectin: A Reflection on Simplicity
Nobel Lecture by William C. Campbell

A Splendid Gift from the Earth: The Origins & Impact of Avermectin
Nobel Lecture by Satoshi Ōmura

Discovery of Artemisinin – A Gift from Traditional Chinese Medicine to the World
Nobel Lecture by Youyou Tu


Spatial Cells in the Hippocampal Formation
Nobel Lecture by John O’Keefe

Grid Cells, Place Cells and Memory
Nobel Lecture by May-Britt Moser

Grid Cells and the Enthorinal Map of Space
Nobel Lecture by Edvard I. Moser


The Principle of Membrane Fusion in the Cell
Nobel Lecture by James E. Rothman

Genetic and Biochemical Dissection of the Secretory Pathway
Nobel Lecture by Randy W. Schekman

A Molecular Machine for Neurotransmitter Release
Nobel Lecture by Thomas C. Südhof


The Egg and the Nucleus: A Battle for Supremacy
Nobel Lecture by Sir John B. Gurdon

A Winding Road to Pluripotency
Nobel Lecture by Shinya Yamanaka


How Mammals Sense Infection: From Endotoxin to the Toll-like Receptors
Nobel Lecture by Bruce A. Beutler

Evolutionary Perspectives of Innate Immunity: Studies with Drosophila
Nobel Lecture by Jules A. Hoffmann

Ralph Steinman and the Discovery of Dendritic Cells
Nobel Lecture for Ralph M. Steinman


Nobel Prize Symposium in Honour of Robert G. Edwards: Bob Edwards and IVF: The Early Days
Nobel Symposium


Telomeres and Telomerase: The Means to the End
Nobel Lecture by Elizabeth H. Blackburn

Telomerase Discovery: The Excitement of Putting Together Pieces of the Puzzle
Nobel Lecture by Carol W. Greider

DNA Ends: Just the Beginning
Nobel Lecture by Jack W. Szostak


The Search for Infectious Causes of Human Cancers: Where and Why?
Nobel Lecture by Harald zur Hausen

HIV: a Discovery Opening the Road to Novel Scientific Achievements and Global Health Improvement
Nobel Lecture by Françoise Barré-Sinoussi

25 Years of Research on AIDS – Lessons and Prospects for Cure and Vaccine
Nobel Lecture by Luc Montagnier


Gene Targeting in the 21st Century: Mouse Models of Human Disease from Cancer to Psychiatric Disorders
Nobel Lecture by Mario R. Capecchi

ES Cells: The Mouse Source – Vehicle for Mammalian Experimental Genetics
Nobel Lecture by Sir Martin J. Evans

Turning Pages
Nobel Lecture by Oliver Smithies


Gene Silencing by Double Stranded RNA
Nobel Lecture by Andrew Z. Fire

Return to the RNAi World: Rethinking Gene Expression and Evolution
Nobel Lecture by Craig C. Mello


Helicobacter Connections
Nobel Lecture by Barry J. Marshall

Helicobacter – The Ease and Difficulty of a New Discovery
Nobel Lecture by J. Robin Warren


Scents and Sensibility: A Molecular Logic of Olfactory Perception
Nobel Lecture by Richard Axel

Unraveling the Sense of Smell
Nobel Lecture by Linda B. Buck


All Science is Interdisciplinary – from Magnetic Moments to Molecules to Men
Nobel Lecture by Paul C. Lauterbur

Snap-Shot MRI
Nobel Lecture by Sir Peter Mansfield


Nature’s Gift to Science
Nobel Lecture by Sydney Brenner

Worms, Life and Death
Nobel Lecture by H. Robert Horvitz

C. elegans: The Cell Lineage and Beyond
Nobel Lecture by John E. Sulston


Yeast and Cancer
Nobel Lecture by Leland H. Hartwell

Protein Synthesis, Proteolysis, and Cell Cycle Transitions
Nobel Lecture by Tim Hunt

Controlling the Cell Cycle
Nobel Lecture by Sir Paul Nurse


A Half-Century of Neurotransmitter Research: Impact on Neurology and Psychiatry
Nobel Lecture by Arvid Carlsson

The Neurobiology of Dopamine Signaling
Nobel Lecture by Paul Greengard

The Molecular Biology of Memory Storage: A Dialog between Genes and Synapses
Nobel Lecture by Eric R. Kandel


Protein Targeting
Nobel Lecture by Günter Blobel


Endothelium-Derived Relaxing Factor: Discovery, Early Studies, and Identification as Nitric Oxide
Nobel Lecture by Robert F. Furchgott

Nitric Oxide: A Unique Endogenous Signaling Molecule in Vascular Biology
Nobel Lecture by Louis J. Ignarro

Discovery of Some of the Biological Effects of Nitric Oxide and Its Role in Cell Signaling
Nobel Lecture by Ferid Murad


Nobel Lecture by Stanley B. Prusiner


Cell Mediated Immunity in Virus Infections
Nobel Lecture by Peter C. Doherty

Cellular Immune Recognition and the Biological Role of Major Transplantation Antigens
Nobel Lecture by Rolf M. Zinkernagel


The Bithorax Complex: The First Fifty Years
Nobel Lecture by Edward B. Lewis

The Identification of Genes Controlling Development in Flies and Fishes
Nobel Lecture by Christiane Nüsslein-Volhard

From Molecular Patterns to Morphogenesis: The Lessons from Drosophila
Nobel Lecture by Eric F. Wieschaus


G Proteins and Regulation of Adenylyl Cyclase
Nobel Lecture by Alfred G. Gilman

Signal Transduction: Evolution of an Idea
Nobel Lecture by Martin Rodbell


An Amazing Distortion in DNA Induced by a Methyltransferase
Nobel Lecture by Richard J. Roberts

Split Genes and RNA Splicing
Nobel Lecture by Phillip A. Sharp


Protein Phosphorylation and Cellular Regulation, II
Nobel Lecture by Edmond H. Fischer

Protein Phosphorylation and Cellular Regulation, I
Nobel Lecture by Edwin G. Krebs


Ion Channels for Communication Between and Within Cells
Nobel Lecture by Erwin Neher

Elementary Steps in Synaptic Transmission Revealed by Currents through Single Ion Channels
Nobel Lecture by Bert Sakmann


The First Successful Organ Transplants in Man
Nobel Lecture by Joseph E. Murray

Bone Marrow Transplantation – Past, Present and Future
Nobel Lecture by E. Donnall Thomas


Retroviruses and Oncogenes II
Nobel Lecture by J. Michael Bishop

Retroviruses and Oncogenes I
Nobel Lecture by Harold E. Varmus


Drugs from Emasculated Hormones: The Principles of Syntopic Antagonism
Nobel Lecture by Sir James W. Black

The Purine Path to Chemotherapy
Nobel Lecture by Gertrude B. Elion

Selective Inhibitors of Dihydrofolate Reductase
Nobel Lecture by George H. Hitchings


Somatic Generation of Immune Diversity
Nobel Lecture by Susumu Tonegawa


Epidermal Growth Factor
Nobel Lecture by Stanley Cohen

The Nerve Growth Factor: Thirty-Five Years Later
Nobel Lecture by Rita Levi-Montalcini


A Receptor-Mediated Pathway for Cholesterol Homeostasis
Nobel Lecture by Michael S. Brown

A Receptor-Mediated Pathway for Cholesterol Homeostasis
Nobel Lecture by Joseph L. Goldstein


The Generative Grammar of the Immune System
Nobel Lecture by Niels K. Jerne

Derivation and Diversification of Monoclonal Antibodies
Nobel Lecture by Georges J.F. Köhler

From the Structure of Antibodies to the Diversification of the Immune Response
Nobel Lecture by César Milstein


The Significance of Responses of the Genome to Challenge
Nobel Lecture by Barbara McClintock


The Prostaglandins: From the Laboratory to the Clinic
Nobel Lecture by Sune K. Bergström

From Studies of Biochemical Mechanisms to Novel Biological Mediators: Prostaglandin Endoperoxides, Thromboxanes and Leukotrienes
Nobel Lecture by Bengt I. Samuelsson

Adventures and Excursions in Bioassay: The Stepping Stones to Prostacyclin
Nobel Lecture by John R. Vane


Some Effects of Disconnecting the Cerebral Hemispheres
Nobel Lecture by Roger W. Sperry

Evolution of Ideas on the Primary Visual Cortex, 1955-1978: A Biased Historical Account
Nobel Lecture by David H. Hubel

The Postnatal Development of the Visual Cortex and the Influence of Environment
Nobel Lecture by Torsten N. Wiesel


The Role of MHC Gene Products in Immune Regulation and Its Relevance to Alloreactivity
Nobel Lecture by Baruj Benacerraf

The Major Histocompatibility Complex in Man – Past, Present, and Future Concepts
Nobel Lecture by Jean Dausset

Studies in Histocompatibility
Nobel Lecture by George D. Snell


Early Two-Dimensional Reconstruction and Recent Topics Stemming from It
Nobel Lecture by Allan M. Cormack

Computed Medical Imaging
Nobel Lecture by Godfrey N. Hounsfield


Decoding the Language of the Bee
Nobel Lecture by Karl von Frisch

Analogy as a Source of Knowledge
Nobel Lecture by Konrad Lorenz

Ethology and Stress Diseases
Nobel Lecture by Nikolaas Tinbergen

Links to more lectures with Nobel Laureates:
Lectures with Nobel Laureates in Physics
Lectures with Nobel Laureates in Chemistry
Lectures with Nobel Laureates in Physiology or Medicine
Lectures with Nobel Laureates in Literature
Lectures with Nobel Peace Prize Laureates
Lectures with Laureates in Economic Sciences