The Nobel Prize in Chemistry 1948
Arne Wilhelm Kaurin
Tiselius was born August 10, 1902, in Stockholm. After the
early loss of his father, the family moved to Gothenburg where he
went to school, and after graduation at the local "Realgymnasium"
in 1921, he studied at the University of
Uppsala, specializing in chemistry. He became research
assistant in The Svedberg's
laboratory in 1925 and obtained his doctor's degree in 1930 on a
thesis "The moving-boundary method of studying the
electrophoresis of proteins" (published in Nova Acta Regiae
Societatis Scientiarum Upsaliensis, Ser. IV, Vol. 7, No. 4)
and was appointed Docent (Assistant Professor) in Chemistry from
1930 on. During the years 1931-1935 Tiselius published a number
of papers on diffusion and adsorption phenomena in naturally
occurring base-exchanging zeolites, and these studies were
continued during a year's visit to H.S. Taylor's laboratory in
Princeton with support of a Rockefeller Foundation Fellowship.
Stimulated by many contacts with American biochemists and
physical chemists during this visit, Tiselius on his return to
Uppsala resumed his interest in proteins, and the application of
physical methods to biochemical problems in general. This led
among other things to a much improved method of electrophoretic
analysis, published in the Transactions of the Faraday
Society, 33 (1937) 524. This method as applied to the study
of serum proteins and to a number of other biochemical problems
kept Tiselius and an increasing number of collaborators occupied
for the following years. In 1938 a special research professorship
was established for Tiselius through a donation to the University
of Uppsala by Major Herbert Jacobsson and his wife. Some space
was put at the disposal of the new professor in the Institute of
Physical Chemistry (Prof. The Svedberg). In 1946 biochemistry was
established as an independent department and in 1950-1952
obtained a new building, the present Institute of
Under the leadership of Tiselius this institute has contributed to the development and improvement of a number of useful methods in biochemistry, such as electrophoresis, chromatography, phase partition, gel filtration, etc. These methods and others have been applied to studies of large molecular weight substances, chiefly proteins and enzymes, but also polysaccharides (dextran) and nucleic acids. There has always been a close contact between the methodological work and the research into special problems where the methods find their application. Tiselius took an active part in the reorganization of scientific research in Sweden in the years following World War II. Thus he was Chairman of the Swedish Natural Science Research Council 1946-1950, and Chairman of the Research Committee of the Swedish Cancer Society 1951-1955. He was President of the International Union of Pure and Applied Chemistry 1951-1955, became Vice President of the Nobel Foundation in 1947 and President since 1960. He has also served as member of the Nobel Committee for Chemistry since 1946.
He was married (1930) with Ingrid Margareta (Greta) Dalén, daughter of city judge Per Dalén of Gothenburg. They have two children: Eva (b. 1932), married to Dr. Torgny Bohlin, Lund; and Per (b. 1934), physician at the Academic Hospital, Uppsala.
From Nobel Lectures, Chemistry 1942-1962, Elsevier Publishing Company, Amsterdam, 1964
This autobiography/biography was written at the time of the award and first published in the book series Les Prix Nobel. It was later edited and republished in Nobel Lectures. To cite this document, always state the source as shown above.
Arne Tiselius died on October 29, 1971.
Copyright © The Nobel Foundation 1948
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