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Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1928
Charles Nicolle

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Charles Nicolle - Facts

Charles Jules Henri Nicolle

Charles Jules Henri Nicolle

Born: 21 September 1866, Rouen, France

Died: 28 February 1936, Tunis, Tunisia

Affiliation at the time of the award: Institut Pasteur, Tunis

Prize motivation: "for his work on typhus"

Field: bacteriology, disease transmission, epidemiology, parasitology

Prize share: 1/1

Work

Typhus fever is a disease that previously caused widespread loss of life during epidemics, especially in connection with wars and disasters. After it was established that several diseases, including malaria, were spread by insects, suspicions arose that this might also be the case with typhus fever. Charles Nicolle noticed that sick people ceased to infect others when they had an opportunity to keep themselves clean. In 1909 he demonstrated that body lice spread typhus fever by successfully transferring the infection among apes by allowing a body louse to first bite infected and then uninfected apes.

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