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Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1958
George Beadle, Edward Tatum, Joshua Lederberg

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George Beadle - Facts

George Wells Beadle

George Wells Beadle

Born: 22 October 1903, Wahoo, NE, USA

Died: 9 June 1989, Pomona, CF, USA

Affiliation at the time of the award: California Institute of Technology (Caltech), Pasadena, CA, USA

Prize motivation: "for their discovery that genes act by regulating definite chemical events"

Field: genetics

Prize share: 1/4

Work

Organisms' metabolism - the chemical processes within its cells - are regulated by substances called enzymes. George Beadle and Edward Tatum proved in 1941 that our genetic code, our genes, govern the formation of enzymes. They exposed a type of mold to x-rays, causing mutations, or changes in its genes. They later succeeded in proving that this led to definite changes in enzyme formation. The conclusion was that each enzyme corresponds to a particular gene.

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