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Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1960
Sir Frank Macfarlane Burnet, Peter Medawar

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Peter Medawar - Facts

Peter Brian Medawar

Peter Brian Medawar

Born: 28 February 1915, Rio de Janeiro, Brazil

Died: 2 October 1987, London, United Kingdom

Affiliation at the time of the award: University College, London, United Kingdom

Prize motivation: "for discovery of acquired immunological tolerance"

Field: immunity

Prize share: 1/2

Work

Our immune system protects us against attacks by microorganisms and rejects foreign tissue. Part of our immunity has a hereditary basis, but part of it is acquired and is not present in the fetus. After Macfarlane Burnet theorized that the ability to distinguish between one's own and foreign tissue is acquired during the fetus stage, Peter Medawar successfully transplanted tissue between mouse fetuses without rejection in 1951. He could perform new transplants on the mice when they became adults, something that did not work when the transplants were not performed during the fetus stage. The results had significance for organ transplants.

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