Edward B. Lewis
Born: 20 May 1918, Wilkes-Barre, PA, USA
Died: 21 July 2004, Pasadena, CA, USA
Affiliation at the time of the award: California Institute of Technology (Caltech), Pasadena, CA, USA
Prize motivation: "for their discoveries concerning the genetic control of early embryonic development"
Field: developmental biology, embryology, genetics
Prize share: 1/3
Among more advanced organisms, life begins when a fertilized egg divides and forms new cells which, in turn, also divide. Initially these cells appear identical, but in time, they begin to change. Some cells go to make up the heart, others nerve paths, and still others strands of hair, for example. Genes regulate this process. Edward Lewis studied fruit flies and in the 1970s he discovered, among other things, that the positions of the flies' bodily organs matched the corresponding genes' positions on the chromosome.
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