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Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1996
Peter C. Doherty, Rolf M. Zinkernagel

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Peter C. Doherty - Facts

Peter C. Doherty

Peter C. Doherty

Born: 15 October 1940, Brisbane, Australia

Affiliation at the time of the award: St. Jude Children's Research Hospital, Memphis, TN, USA

Prize motivation: "for their discoveries concerning the specificity of the cell mediated immune defence"

Field: immunity

Prize share: 1/2

Work

When the body's cells are attacked by viruses, the immune system begins killing the infected cells. By studying mice, Peter Doherty and Rolf Zinkernagel proved in 1973 how the immune system recognizes virus-ridden cells. A kind of white blood cell, T-cells, kills the virus-ridden cells, but only if they recognize both the foreign substances, viruses, and certain substances from the body's own cells. The discovery has provided an important basis for vaccines and medicines for infectious diseases, but also for inflammatory diseases and cancer.

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