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Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1971
Earl W. Sutherland, Jr.

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Earl W. Sutherland, Jr. - Facts

Earl W. Sutherland, Jr.

Earl W. Sutherland, Jr.

Born: 19 November 1915, Burlingame, KS, USA

Died: 9 March 1974, Miami, FL, USA

Affiliation at the time of the award: Vanderbilt University, Nashville, TN, USA

Prize motivation: "for his discoveries concerning the mechanisms of the action of hormones"

Field: cell physiology, endocrinology, metabolism

Prize share: 1/1

Work

Signals between different parts of the body are conveyed by small electrical impulses and by chemical substances, hormones and signal substances. Communication also takes place between different cell parts. Earl Sutherland investigated how hormones, especially adrenaline, work. He showed how signals from one cell to another are conveyed by a messenger - the hormone - and how signals within the cell are then conveyed by another messenger. Around 1960 he showed how cyclic adenosine monophosphate (cAMP) serves as the secondary messenger within the cell.

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