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Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1972
Gerald M. Edelman, Rodney R. Porter

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Gerald M. Edelman - Facts

Gerald M. Edelman

Gerald M. Edelman

Born: 1 July 1929, New York, NY, USA

Died: 17 May 2014, La Jolla, CA, USA

Affiliation at the time of the award: Rockefeller University, New York, NY, USA

Prize motivation: "for their discoveries concerning the chemical structure of antibodies"

Field: immunity

Prize share: 1/2

Work

Our immune system protects us from attacks by microorganism and poisons, in part through formation of antibodies in the blood that neutralize foreign substances. Gerald Edelmann and Rodney Porter separately researched the chemical composition of antibodies. Using various chemical methods, they split up antibodies into smaller parts and mapped their biological effects. In 1959, this allowed them to determine the structure of antibodies. Antibodies are made up of two smaller and two larger polypeptide chains that form a Y-shaped structure.

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