Born: 13 June 1870, Soignies, Belgium
Died: 6 April 1961, Brussels, Belgium
Affiliation at the time of the award: Brussels University, Brussels, Belgium
Prize motivation: "for his discoveries relating to immunity"
Jules Bordet received his Nobel Prize one year later, in 1920.
Prize share: 1/1
Our immune system protects us from attacks by microorganisms and poisonous substances. The blood includes factors or bodies that destroy bacteria. Through studies of cholera in 1896, Jules Bordet showed that this depends on the collaboration of two types of factors in the blood: antibodies formed by immunization against specific bacteria and complement proteins that also exist in blood that is not immunized. Antibodies and complement proteins are bound to one another, which can be used to detect certain diseases, including syphilis.
"for their discoveries concerning the specificity of the cell mediated immune defence"
"for theories concerning the specificity in development and control of the immune system and the discovery of the principle for production of monoclonal antibodies"
"for his discovery of the genetic principle for generation of antibody diversity"