Sir Charles Scott Sherrington
Born: 27 November 1857, London, United Kingdom
Died: 4 March 1952, Eastbourne, United Kingdom
Affiliation at the time of the award: University of Oxford, Oxford, United Kingdom
Prize motivation: "for their discoveries regarding the functions of neurons"
Prize share: 1/2
Our bodily functions are governed by our nervous system, which consists of many nerve cells with extensions, or nerve fibers, which form a system of connections between the brain and spinal cord and the rest of the body. Certain stimuli of nerve cells give rise to unconscious muscular movements, or reflexes. In the 1890s Charles Sherrington showed how muscular contractions are followed by relaxation and how different reflexes are part of a complicated interplay in which the spinal cord and brain process nerve impulses and turn them into new impulses to muscles and organs.
"for their discoveries relating to the highly differentiated functions of single nerve fibres"
"for their discoveries relating to chemical transmission of nerve impulses"
"for their discoveries concerning the humoral transmittors in the nerve terminals and the mechanism for their storage, release and inactivation"