Ulf von Euler
Born: 7 February 1905, Stockholm, Sweden
Died: 9 March 1983, Stockholm, Sweden
Affiliation at the time of the award: Karolinska Institutet, Stockholm, Sweden
Prize motivation: "for their discoveries concerning the humoral transmittors in the nerve terminals and the mechanism for their storage, release and inactivation"
Prize share: 1/3
Human and animal nervous systems consist of a large variety of cells with long nerve fibers. Small electrical currents and special chemical substances (neurotransmitters) are passed between cells through contacts (synapses). In 1947 Ulf von Euler discovered the neurotransmitter norepinephrine, which plays an important role in producing fight-or-flight signals. He subsequently showed that norepinephrine is formed and stored in packages, or vesicles, sent between neurons via synapses.
"for their discoveries concerning the ionic mechanisms involved in excitation and inhibition in the peripheral and central portions of the nerve cell membrane"
"for their discoveries relating to the highly differentiated functions of single nerve fibres"
"for their discoveries relating to chemical transmission of nerve impulses"