Born: 12 June 1942, Stuttgart, Germany
Affiliation at the time of the award: Max-Planck-Institut für medizinische Forschung, Heidelberg, Federal Republic of Germany
Prize motivation: "for their discoveries concerning the function of single ion channels in cells"
Field: cell physiology
Prize share: 1/2
One of the fundamental processes of life is the transit of charged atoms - ions - through the surface layer of cells that make up organisms. Among other things, this transit is of crucial importance for the transfer of signals in nerves and muscles so that the body functions. Around 1980 Bert Sakmann and Erwin Neher developed a method for measuring the extremely weak currents involved in ion transits. These results confirmed that the transit occurs through ion channels - molecules on the surface of cells that under certain conditions allow ions to pass through.
"for their discoveries concerning magnetic resonance imaging"
"for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells"
"for their discovery of G-proteins and the role of these proteins in signal transduction in cells"