Chemistry
The Nobel Prize in Chemistry 2004
The Nobel Prize in Chemistry 2004 Ubiquitin This is what the actual label looks like. It consists of a short polypeptide chain, a small protein that is so common in the cells of different organisms that it was early named ubiquitin, from the Latin ubique, ‘everywhere’. This protein…
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The Nobel Prize in Chemistry 2004 The most common reason for miscarriage is an error when the mother’s and the father’s chromosomes are to be separated in the formation of sex cells. Ubiquitin-marking plays an important role here. The picture shows a calf embryo. How are sex cells…
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The Nobel Prize in Chemistry 2004 What proteins are marked? Surprisingly many of the proteins created in the cell are faulty from the start. They must be broken down and rebuilt since they can damage the organism. But perhaps the most important reason for a cell to get…
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The Nobel Prize in Chemistry 2004 The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2004 “for the discovery of ubiquitin-mediated protein degradation” jointly to Aaron Ciechanover, Avram Hershko and Irwin Rose It has long been clear how proteins are built up in the…
moreCredits and References for the 1997 Chemistry Nobel Poster
Editors: Solgerd Björn-Rasmussen and Margareta Wiberg Roland, The Royal Swedish Academy of Sciences. Authors: Prof. Anders Liljas, Lund University, Member of the Nobel Committee for Chemistry and Dr. Lars Hederstedt and Dr. Salam Al-Karadaghi, Lund University. Layout and illustrations: Kjell Lundin, Explicare AB. Printed by: Tryckindustri 1997. Photos: Jilly Wendell and…
moreFurther reading
(press release), The Royal Swedish Academy of Sciences. Boyer, P.D., The binding change mechanism for ATP synthase – Some probabilities and possibilities, Biochimica et Biophysica Acta (1993) 1140, 215-250. Abrahams, J.P., Leslie, A.G., Lutter, R., and Walker, J.E., Structure at 2.8 Å resolution of F1-ATPase from bovine heart mitochondria, Nature (1994) 370, 621-628.…
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