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Ralph M. Steinman – Nobel diploma

Copyright © The Nobel Foundation 2011
Calligrapher: Susan Duvnäs
Book binder: Ingemar Dackéus
Photo reproduction: Lovisa Engblom

Ralph M. Steinman – Prize presentation

Watch a video clip of Mrs Claudia Steinman receiving the Nobel Medal and Diploma on behalf of the late Professor Ralph M. Steinman during the Nobel Prize Award Ceremony at the Concert Hall in Stockholm, Sweden, on 10 December 2011.

Ralph M. Steinman – Photo gallery

Mrs Claudia Steinman receiving the Nobel Medal and Diploma on behalf of the late Professor Ralph M. Steinman

Mrs Claudia Steinman receiving the Nobel Medal and Diploma on behalf of the late Professor Ralph M. Steinman from His Majesty King Carl XVI Gustaf of Sweden at the Stockholm Concert Hall, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Frida Westholm

Mrs Claudia Steinman blows a kiss after receiving the Nobel Medal and Diploma on behalf of the late Professor Ralph M. Steinman

Mrs Claudia Steinman blew a kiss after receiving the Nobel Medal and Diploma on behalf of the late Professor Ralph M. Steinman at the Stockholm Concert Hall, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Frida Westholm

Family and friends of he late Professor Ralph M. Steinman assembled after the Nobel Prize Award Ceremony

Family and friends of he late Professor Ralph M. Steinman assembled after the Nobel Prize Award Ceremony at the Stockholm Concert Hall, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Lina Göransson

Dan Shechtman arrives at the Nobel Banquet accompanied by Mrs Claudia Steinman, wife of the late Medicine Laureate Ralph M. Steinman

Mrs Claudia Steinman, wife of the late Medicine Laureate Ralph M. Steinman, arrives at the Nobel Banquet accompanied by Chemistry Laureate Dan Shechtman. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Mrs Claudia Steinman, wife of the late Medicine Laureate Ralph M. Steinman, and Chemistry Laureate Dan Shechtman at the Nobel Banquet

Mrs Claudia Steinman, wife of the late Medicine Laureate Ralph M. Steinman, and Chemistry Laureate Dan Shechtman at the Nobel Banquet, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Michel C. Nussenzweig delivering a Nobel Lecture on behalf of the late Ralph M. Steinman

Michel C. Nussenzweig delivering a Nobel Lecture on behalf of the late Ralph M. Steinman in the Jacob Berzelius Lecture Hall at Karolinska Institutet, 7 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Mrs Claudia Steinman, wife of the late Professor Ralph M. Steinman, with daughter Lesley and grandson Robert

Mrs Claudia Steinman (left), wife of the late Professor Ralph M. Steinman, with daughter Lesley (right) and grandson Robert at the Nobel Museum in Stockholm, 6 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Portrait of Professor Ralph M. Steinman

Portrait of Professor Ralph M. Steinman.

Photo: Zach Veilleux/Rockefeller University

Professor Ralph M. Steinman, 2011 Nobel Laureate in Physiology or Medicine, in his laboratory

Professor Ralph M. Steinman, 2011 Nobel Laureate in Physiology or Medicine, in his laboratory.

Photo: Zach Veilleux/Rockefeller University

Professor Ralph M. Steinman in his laboratory

Professor Ralph M. Steinman in his laboratory.

Photo: Courtesy Rockefeller University

High-resolution image of a dendritic cell made by Ralph Steinman in 1973

High-resolution image of a dendritic cell made by Ralph M. Steinman in 1973.

Photo: Ralph M. Steinman

Ralph M. Steinman's wife, Claudia Steinman, speaks with reporters after the announcement of the 2011 Nobel Prize in Physiology or Medicine.

Ralph M. Steinman's wife, Claudia Steinman, speaks with reporters after the announcement of the 2011 Nobel Prize in Physiology or Medicine.

Photo: Zach Veilleux/Rockefeller University

Ralph M. Steinman's wife, Claudia Steinman, speaks with reporters after the announcement of the 2011 Nobel Prize in Physiology or Medicine.

Ralph M. Steinman's daughter, Alexis Steinman, speaks with reporters after the announcement of the 2011 Nobel Prize in Physiology or Medicine.

Photo: Zach Veilleux/Rockefeller University

Michel Nussenzweig, Ralph M. Steinman's first student and longtime collaborator, addresses reporters at the press conference

Michel Nussenzweig, Ralph M. Steinman's first student and longtime collaborator, addresses reporters at the press conference after the announcement of the 2011 Nobel Prize in Physiology or Medicine.

Photo: Zach Veilleux/Rockefeller University

Ralph M. Steinman – Nobel Lecture

Ralph Steinman and the Discovery of Dendritic Cells

Michel C. Nussenzweig delivered a Nobel Lecture on behalf of the late Ralph M. Steinman on 7 December 2011 at Karolinska Institutet in Stockholm. He was introduced by Professor Lars Klareskog, Chairman of the Nobel Assembly

Presentation

Michel C. Nussenzweig delivered a Nobel Lecture on behalf of the late Ralph M. Steinman on 7 December 2011 at Karolinska Institutet in Stockholm. He was introduced by Professor Lars Klareskog, Chairman of the Nobel Assembly

Read the Nobel Lecture
Pdf 14 MB

Lecture Slides
Pdf 5.6 MB

Jules A. Hoffmann – Banquet speech

Jules A. Hoffmann’s speech at the Nobel Banquet, 10 December 2011.

Your Majesties,
Your Royal Highnesses,
Honoured Guests,

On behalf of the awardees of the Nobel Prize in Physiology or Medicine, I first wish to express our deeply felt appreciation of the exceptional honor which is bestowed on us today.

We are delighted that the Nobel Committee chose to highlight this year the field of immunity in its cellular, molecular, genetic, functional and phylogenetic contours, from insects to mammals. Although the awards recognize our personal contributions, we wish to stress that a large and excellent scientific community has contributed to the significant advances made over the last decades in this field and we address our warm appreciation tonight to all our colleagues, associates and students worldwide.

It is well understood today that the spectacular increase of human life expectancy, which started in the second half of the 19th century, is to a very large extent the result of better protection against microbial and parasitic infections: better hygiene, vaccination, and antibiotics are credited for this remarkable progress. Nevertheless, in the sphere of antimicrobial host defenses, we unfortunately live in an environment where infectious agents can rapidly evolve and pose a constant threat to the well-being of humankind. This situation requires that we remain ever vigilant and collectively continue our efforts toward a better understanding of:

– how our bodies sense invading microorganisms,
– how we activate the appropriate counter-measures and
– how we can ourselves adapt to strategies by which the invaders try to elude our defenses.

We hope that the studies highlighted today, will contribute to the development of new ways to protect humans against infection, now and in the future.

We are deeply indebted to our co-workers, without whose enthusiastic participation our studies would not have come to fruition. We are also indebted to those who, in our Universities and Research Agencies, have generously funded our studies and given us the opportunities to embark on difficult, high-risk projects without guarantees of success. Finally, we acknowledge with deep respect the strong influence of exceptional mentors. We also recognize with great emotion the warmth and strength provided to us by our families over many years.

I wish to end this address with a special thought to our friend, colleague and co-laureate Ralph Steinman, whom we all miss to-night with great sadness – his place in the firmament of Science is for ever assured which gives some solace to family and friends.

Thank you for your kind attention.

Bruce A. Beutler – Prize presentation

Watch a video clip of the 2011 Nobel Laureate in Physiology or Medicine, Bruce A. Beutler, receiving his Nobel Prize medal and diploma during the Nobel Prize Award Ceremony at the Concert Hall in Stockholm, Sweden, on 10 December 2011.

Jules A. Hoffmann – Prize presentation

Watch a video clip of the 2011 Nobel Laureate in Physiology or Medicine, Jules A. Hoffmann, receiving his Nobel Prize medal and diploma during the Nobel Prize Award Ceremony at the Concert Hall in Stockholm, Sweden, on 10 December 2011.

Jules A. Hoffmann – Photo gallery

Jules A. Hoffmann receiving his Nobel Prize from His Majesty King Carl XVI Gustaf

Jules A. Hoffmann receiving his Nobel Prize from His Majesty King Carl XVI Gustaf of Sweden at the Stockholm Concert Hall, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Frida Westholm

Jules A. Hoffmann after receiving his Nobel Prize at the Stockholm Concert Hall

Jules A. Hoffmann after receiving his Nobel Prize at the Stockholm Concert Hall, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Frida Westholm

Jules A. Hoffmann arrives at the Nobel Banquet accompanied by Mrs Nancy Joy Riess, wife of Physics Laureate Adam G. Riess

Jules A. Hoffmann arrives at the Nobel Banquet accompanied by Mrs Nancy Joy Riess, wife of Physics Laureate Adam G. Riess. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Jules A. Hoffmann and Mrs Nancy Joy Riess, wife of Physics Laureate Adam G. Riess, at the Nobel Banquet

Jules A. Hoffmann and Mrs Nancy Joy Riess, wife of Physics Laureate Adam G. Riess, at the Nobel Banquet, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Dan Shechtman at Nobel Media's taping of the TV-program Nobel Minds in the Bernadotte Library at the Royal Palace, 9 December 2011

Recording of Nobel Media's TV-program 'Nobel Minds', hosted by Zeinab Badawi, BBC World News, in the Bernadotte Library at the Royal Palace, 9 December 2011.

Photo: Claes Löfgren Copyright Nobel Media AB 2011

Jules A. Hoffmann at Nobel Media's taping of the TV-program Nobel Minds in the Bernadotte Library at the Royal Palace, 9 December 2011

Jules A. Hoffmann at Nobel Media's recording of the TV-program 'Nobel Minds' in the Bernadotte Library at the Royal Palace, 9 December 2011.

Photo: Claes Löfgren Copyright Nobel Media AB 2011

Jules A. Hoffmann delivering his Nobel Lecture in the Jacob Berzelius Lecture Hall at Karolinska Institutet

Jules A. Hoffmann delivering his Nobel Lecture in the Jacob Berzelius Lecture Hall at Karolinska Institutet, 7 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Jules A. Hoffmann (left) and Bruce A. Beutler (right) during their interview with Nobelprize.org

Jules A. Hoffmann (left) and Bruce A. Beutler (right) during their interview with Nobelprize.org on 6 December 2011. Copyright © Nobel Media 2011
Photo: Frida Westholm

Jules A. Hoffmann autographs a chair

Like many Nobel Laureates before him, Jules A. Hoffmann autographs a chair at Bistro Nobel at the Nobel Museum in Stockholm, 6 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Portrait of Professor Jules A. Hoffmann

Portrait of Professor Jules A. Hoffmann.

Photo: Kindly provided by CNRS Photo Library/Pascal Disdier

Bruce A. Beutler – Photo gallery

Bruce A. Beutler receiving his Nobel Prize from His Majesty King Carl XVI Gustaf

Bruce A. Beutler after receiving his Nobel Prize at the Stockholm Concert Hall

Bruce A. Beutler after receiving his Nobel Prize at the Stockholm Concert Hall, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Frida Westholm

Bruce A. Beutler arrives at the Nobel Banquet accompanied by Psychiatrist Ylwa Westerberg

Bruce A. Beutler arrives at the Nobel Banquet accompanied by Psychiatrist Ylwa Westerberg. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Bruce A. Beutler and Psychiatrist Ylwa Westerberg at the Nobel Banquet

Bruce A. Beutler and Psychiatrist Ylwa Westerberg at the Nobel Banquet, 10 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Eleven of the thirteen 2011 Nobel Laureates assembled for a group photo during their visit to the Nobel Foundation in Stockholm, 12 December 2011

Eleven of the thirteen 2011 Nobel Laureates assembled for a group photo during their visit to the Nobel Foundation in Stockholm, 12 December 2011. Back row, left to right: Nobel Peace Prize Laureates Tawakkol Karman and Leymah Gbowee, Nobel Laureates in Physics Brian P. Schmidt, Saul Perlmutter and Adam G. Riess, Nobel Laureate in Chemistry Dan Shechtman and Nobel Laureate in Physiology or Medicine Bruce A. Beutler. Front row, left to right: Nobel Peace Prize Laureate Ellen Johnson Sirleaf, Laureate in Economic Sciences Christopher A. Sims, Nobel Laureate in Literature Tomas Tranströmer and Laureate in Economic Sciences Thomas J. Sargent.

© The Nobel Foundation 2011. Photo: Orasisfoto

Dan Shechtman at Nobel Media's taping of the TV-program Nobel Minds in the Bernadotte Library at the Royal Palace, 9 December 2011

Recording of Nobel Media's TV-program 'Nobel Minds', hosted by Zeinab Badawi, BBC World News, in the Bernadotte Library at the Royal Palace, 9 December 2011.

Photo: Claes Löfgren Copyright Nobel Media AB 2011

Bruce A. Beutler at Nobel Media's taping of the TV-program 'Nobel Minds' in the Bernadotte Library at the Royal Palace, 9 December 2011

Bruce A. Beutler at Nobel Media's recording of the TV-program 'Nobel Minds' in the Bernadotte Library at the Royal Palace, 9 December 2011.

Photo: Claes Löfgren Copyright Nobel Media AB 2011

Bruce A. Beutler delivering his Nobel Lecture in the Jacob Berzelius Lecture Hall at Karolinska Institutet

Bruce A. Beutler delivering his Nobel Lecture in the Jacob Berzelius Lecture Hall at Karolinska Institutet, 7 December 2011. Copyright © The Nobel Foundation 2011
Photo: Orasisfoto

Jules A. Hoffmann (left) and Bruce A. Beutler (right) during their interview with Nobelprize.org

Jules A. Hoffmann (left) and Bruce A. Beutler (right) during their interview with Nobelprize.org on 6 December 2011. Copyright © Nobel Media 2011
Photo: Frida Westholm

Bruce A. Beutler autographs a chair

Bruce Beutler with colleague in the laboratory

Bruce Beutler (left) with colleague Yu Xia (right) in the laboratory.

Photo: Michael Balderas. Courtesy: The Scripps Research Institute.

Bruce A. Beutler – Nobel Lecture

How Mammals Sense Infection: From Endotoxin to the Toll-like Receptors

Bruce A. Beutler delivered his Nobel Lecture on 7 December 2011 at Karolinska Institutet in Stockholm. He was introduced by Professor Lars Klareskog, Chairman of the Nobel Assembly.

Presentation

Bruce A. Beutler delivered his Nobel Lecture on 7 December 2011 at Karolinska Institutet in Stockholm. He was introduced by Professor Lars Klareskog, Chairman of the Nobel Assembly.

Lecture slides
Pdf 19.6 MB

Animation of a complex of LPS, MD-2 and TLR4 rotating in space.
Animation

Read the Nobel Lecture
Pdf 13.17 MB