Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Chemistry 1972
Christian Anfinsen, Stanford Moore, William H. Stein

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William H. Stein - Facts

William H. Stein

William H. Stein

Born: 25 June 1911, New York, NY, USA

Died: 2 February 1980, New York, NY, USA

Affiliation at the time of the award: Rockefeller University, New York, NY, USA

Prize motivation: "for their contribution to the understanding of the connection between chemical structure and catalytic activity of the active centre of the ribonuclease molecule"

Field: analytical biochemistry, biochemistry

Prize share: 1/4


The genetic information of an organism is stored in DNA molecules which, via RNA molecules, are converted during the formation of proteins. The chemical processes inside cells are controlled by a type of protein called enzymes. William Stein and Stanford Moore studied the enzyme ribonuclease, which divides RNA into smaller components. In the late 1950s, the pair succeeded in providing a detailed understanding of the enzyme's active center and in elucidating the connection between the structure of the molecule and its ability to speed up biochemical reactions.

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