Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Chemistry 2003
Peter Agre, Roderick MacKinnon

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The Laureates
Peter Agre, Johns Hopkins University School of Medicine
Roderick MacKinnon, The Rockefeller University
Animations: Water channels
Original papers
"Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein". Preston, G.M., Carroll, T.P., Guggino, W.B., and Agre, P. (1992). Science 256, 385-387.
"Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein". Zeidel, M.L., Ambudkar, S.V., Smith, B.L., and Agre, P. (1992). Biochemistry 31, 7436-7440.
"The structure of the potassium channel: Molecular basis of K+ conduction and selectivity". D.A. Doyle, J. Morais Cabral, R.A. Pfuetzner, A. Quo, J.M. Gulbis, S.L. Cohen, B.T. Chait and R. MacKinnon. Science 280 (1998) 69-77.
"Energetic optimization of ion conduction rate by the K+ selectivity filter". J.H. Morais-Cabral, Y. Zhou and R. MacKinnon. Nature 414 (2001) 37-47.
"Crystal structure and mechanism of a calcium-gated potassium channel", Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B.T., and MacKinnon, R. (2002). Nature 417, 515-522.
Other articles
"Aquaporin Water Channels: Molecular Mechanisms for Human Diseases". P. Agre and D. Kozono, FEBS Letters, papers in press, October 2003.
"Aquaporin Water Channels: Atomic structure and molecular dynamics meet clinical medicine". D. Kozono, M. Yasui, L.S. King and P. Agre. The Journal of Clinical Investigation 109 (2002) 1395-1399.
"Potassium Channels". R. MacKinnon FEBS Letters, papers in press, October 2003.


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