Nobel Prizes and Laureates

Nobel Prizes and Laureates

The Nobel Prize in Physiology or Medicine 1949
Walter Hess, Egas Moniz

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Walter Hess - Facts

Walter Rudolf Hess

Walter Rudolf Hess

Born: 17 March 1881, Frauenfeld, Switzerland

Died: 12 August 1973, Ascona, Switzerland

Affiliation at the time of the award: University of Zurich, Zurich, Switzerland

Prize motivation: "for his discovery of the functional organization of the interbrain as a coordinator of the activities of the internal organs"

Field: neurophysiology

Prize share: 1/2


The diencephalon of both human and animal brains has cells that govern many behaviors. During the 1930s Walter Hess inserted a narrow metal thread into different parts of anesthetized cats' hypothalamus, an area on the underside of the diencephalon. When the cats awoke, he could trigger different behaviors with weak electrical impulses to different parts of the hypothalamus - not just simple reactions but complex behaviors. Among other things, the cats could be made to display defensive and aggressive behaviors and to curl up and go to sleep.

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