Nobel Prize

Swedish 8 oktober 2003 Allt levande består av celler. En enda människa har lika många celler som stjärnorna i en galax, ungefär 100 miljarder. De olika cellerna, t.ex. muskelceller, njurceller och nervceller, samverkar i ett intrikat system i var och en av oss. Årets Nobelpristagare i kemi, Peter Agre och Roderick MacKinnon, har bidragit till…

The Laureates Peter Agre, Johns Hopkins University School of Medicine , The Rockefeller University Animations Original papers “Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein”. Preston, G.M., Carroll, T.P., Guggino, W.B., and Agre, P. (1992). Science 256, 385-387. “Reconstitution of functional water channels in liposomes containing purified red cell CHIP28 protein”.…

French le 8 octobre 2003 a décidé d’attribuer le Prix Nobel de Chimie de l’année 2003, »pour des découvertes concernant des canaux dans la membrane cellulaire» pour moitié à Peter Agre Johns Hopkins University School of Medicine, Baltimore, USA »pour la découverte des canaux à eau», et pour l’autre moitié à Roderick MacKinnon Howard Hughes…

Swedish 8 oktober 2003 har beslutat utdela Nobelpriset i kemi år 2003 ”för upptäckter rörande kanaler i cellmembran” med hälften av priset till Peter Agre Johns Hopkins University School of Medicine, Baltimore, USA, ”för upptäckten av vattenkanaler” och den andra hälften till Roderick MacKinnon Howard Hughes Medical Institute, The Rockefeller University, New York, USA ”för…

  The Nobel Prize in Chemistry 2003             Earlier Nobel Laureates of great importance in the development leading up to this year’s award:               1901 1909 1963 1991 1997 2003             1901 van’t Hoff receives the Nobel Prize in…

  The Nobel Prize in Chemistry 2003           Roderick MacKinnon Roderick MacKinnon is Professor of Molecular Neurobiology and Biophysics at The Rockefeller University in New York, USA.   Ion channels: Tiny molecular machines     In 1998 Roderick MacKinnon for the first time determined at high resolution the structure of an…

  The Nobel Prize in Chemistry 2003         Credits     Editors: Gunnar von Heijne, member of the Nobel Committee for Chemistry, Bengt Nordén, chairman of the Nobel Committee for Chemistry and Eva Krutmeijer and Malin Lindgren, Information Department, The Royal Swedish Academy of Sciences. Layout and Illustrations: Typoform Printing: Tryckindustri 2003…

  The Nobel Prize in Chemistry 2003         The cell’s contact with the outer world     The wall that separates a cell from its surroundings – the membrane – is not an impermeable shell. It is pierced through by various sorts of channel. The channels consist of proteins, each with its…

  The Nobel Prize in Chemistry 2003         Further Reading     WATER CHANNELS Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein by G.M. Preston, T.P. Carroll, W.B. Guggino, and P. Agre, Science 256 (1992), p. 385-387 Molecular Mechanisms for Human Diseases by P. Agre and D. Kozono,…

  The Nobel Prize in Chemistry 2003           Peter Agre Peter Agre is Professor of Biological Chemistry and Professor of Medicine at Johns Hopkins School of Medicine in Baltimore, USA.   Water channels: The cell leaks like a sieve     How does water actually pass through the cell membrane? The…