Julius Wagner-Jauregg


Julius Wagner-Jauregg

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Julius Wagner-Jauregg
The Nobel Prize in Physiology or Medicine 1927

Born: 7 March 1857, Wels, Austria

Died: 27 September 1940, Vienna, Austria

Affiliation at the time of the award: Vienna University, Vienna, Austria

Prize motivation: “for his discovery of the therapeutic value of malaria inoculation in the treatment of dementia paralytica”

Prize share: 1/1


General paralysis is a stage in syphilis when the brain and psyche are attacked and the patient ends up in a lethargic and paralytic state that can end in death. As far back as antiquity, people noted that mental illnesses could be ameliorated by fevers. In 1917 Julius Wagner-Jauregg exposed patients to malaria-infected blood and could in this way cure or alleviate general paralysis. The malaria was of a type that was comparatively innocuous, and consequently the patient’s health could be improved.

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