Andrew V. Schally
The Nobel Prize in Physiology or Medicine 1977
Born: 30 November 1926, Wilno, Poland (now Vilnius, Lithuania)
Affiliation at the time of the award: Veterans Administration Hospital, New Orleans, LA, USA
Prize motivation: “for their discoveries concerning the peptide hormone production of the brain”
Prize share: 1/4
Hormones are substances that convey signals between different parts of the body and regulate their functions. Around the pituitary in the brain, Releasing hormones serve to release other hormones and are formed around the pituitary gland. The releasing hormones occur in very small amounts. From large quantities of pig brains and lamb brains respectively, Andrew Schally and Roger Guillemin separately extracted a sufficient amount of releasing hormone to determine its structure in 1969. They subsequently were able to produce it with chemical methods.
Their work and discoveries range from paleogenomics and click chemistry to documenting war crimes.
See them all presented here.