The Nobel Assembly at the Karolinska Institute in Stockholm, Sweden, has awarded the Nobel Prize in Physiology or Medicine for 1998 to Robert F Furchgott, Louis J Ignarro and Ferid Murad for their discoveries concerning “the nitric oxide as a signalling molecule in the cardiovascular system”.
|Robert F Furchgott, born 1916
Dept. of Pharmacology,
SUNY Health Science Center
|Louis J Ignarro, born 1941
Dept. of Molecular and Medical Pharmacology
UCLA School of Medicine
|Ferid Murad, born 1936
Dept. of Integrative Biology
Pharmacology and Physiology
University of Texas Medical School, Houston
A New Principle
Nitric Oxide, NO, is a short-lived, endogenously produced gas that acts as a signalling molecule in the body. Signal transmission by a gas, produced by one cell, which penetrates membranes and regulates the function of other cells is an entirely new principle for signalling in the human organism.
Their work and discoveries range from cancer therapy and laser physics to developing proteins that can solve humankind’s chemical problems. The work of the 2018 Nobel Laureates also included combating war crimes, as well as integrating innovation and climate with economic growth. Find out more.