Nobel Prize

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Presentation Speech by Professor W. Wernstedt, Dean of the , December 10, 1927 Your Majesty, Your Royal Highnesses, Ladies and Gentlemen. Few diseases have the power of inspiring fear to the same degree as cancer. However, who would be surprised at that? How many times is this affliction not synonymous with a long, painful and…

KAROLINSKA INSTITUTET October 1977 has decided that the Nobel Prize in Physiology or Medicine for 1977 should be divided, one half being awarded jointly to Roger Guillemin and Andrew Schally for their discoveries concerning “the peptide hormone production of the brain” and the other half to Rosalyn Yalow for “the development of radioimmunoassays of peptid…

  Presentation Speech by Professor Börje Cronholm of the Karolinska Medico-Chirurgical Institute Translation from the Swedish text Your Majesty, Your Royal Highnesses, Ladies and Gentlemen, Animal behavior has fascinated man since time immemorial as can be witnessed by the important role of animals in myths, fairy-tales and fables. However, for too long man has tried…

In many inherited diseases, proteins are mislocalized in the cell due to errors in targeting signals and transport. One example is “primary hyperoxaluria,” a rare disease, which results in kidney stones already at an early age. A signal in the enzyme alanine:glyoxylate aminotransferase normally directs it to the peroxisome. In patients, this signal is altered…

  The Nobel Assembly at the Karolinska Institute in Stockholm, Sweden, has awarded the Nobel Prize in Physiology or Medicine for 1995 to Edward B. Lewis, Christiane Nüsslein-Volhard and Eric Wieschaus for their discoveries concerning “the genetic control of early embryonic development”.   From Egg to Adult Fly   The adult fly consists of head,…

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Charles Richet was born on August 26, 1850, in Paris. He was the son of Alfred Richet, Professor of Clinical Surgery in the Faculty of Medicine, Paris, and his wife Eugenie, née Renouard. He studied in Paris, becoming Doctor of Medicine in 1869, Doctor of Sciences in 1878 and Professor of Physiology from 1887 onwards…

Charles Scott Sherrington was born on November 27, 1857, at Islington, London. He was the son of James Norton Sherrington, of Caister, Great Yarmouth, who died when Sherrington was a young child. Sherrington’s mother later married Dr. Caleb Rose of Ipswich, a good classical scholar and a noted archaeologist, whose interest in the English artists…