Nobel Prize

Mary E. Brunkow’s speech at the Nobel Prize banquet, 10 December 2025 Your Majesties,Your Royal Highnesses,Excellences,Dear Laureates,Ladies and gentlemen, On behalf of Professors and , I would like to thank the Nobel Assembly at Karolinska Institute and the Nobel Foundation.  On October 6, while I was desperately trying to sleep through the 1:00am scam calls…

Watch the Nobel Prize award ceremony from Konserthuset Stockholm, Sweden, 10 December 2025

Presented by Professor Olle KämpeMember of the Nobel Assembly at Karolinska InstitutetChair of the Nobel Committee for Physiology or Medicine Your Majesties, Your Royal Highnesses,Esteemed Nobel Prize Laureates, Ladies and Gentlemen, This year’s Nobel Prize in Physiology or Medicine honours discoveries that explain how our immune system is agile, adaptable and skilful in defending us…

Calligrapher: Susan DuvnäsBook binder: Leonard Gustafssons Bokbinderi ABPhoto reproduction: Dan Lepp© The Nobel Foundation 2025

Calligrapher: Susan DuvnäsBook binder: Leonard Gustafssons Bokbinderi ABPhoto reproduction: Dan Lepp© The Nobel Foundation 2025

Calligrapher: Susan DuvnäsBook binder: Leonard Gustafssons Bokbinderi ABPhoto reproduction: Dan Lepp© The Nobel Foundation 2025

The immune system’s security guards What happens if our immune system attacks our own cells? The Nobel Prize in Physiology or Medicine 2025 is about our immune system. The immune system protects us from viruses, bacteria and other kinds of microorganisms. The Nobel Prize laureates Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi have discovered…

Translating Basic Science to Therapeutic Opportunities: the Treg Example Fred Ramsdell delivered his Nobel Prize lecture at Aula Medica, Karolinska Institutet in Stockholm on 7 December 2025. He was introduced by professor Gunilla Karlsson Hedestam, member of the Nobel Assembly at Karolinska Institutet.

FoxP3/Scurfin: A Key Driver of Peripheral Immune Tolerance Mary E. Brunkow delivered her Nobel Prize lecture at Aula Medica, Karolinska Institutet in Stockholm on 7 December 2025. She was introduced by professor Gunilla Karlsson Hedestam, member of the Nobel Assembly at Karolinska Institutet.

Regulatory T cells for Immune Tolerance: Discovery and Clinical Prospects Shimon Sakaguchi delivered his Nobel Prize lecture at Aula Medica, Karolinska Institutet in Stockholm on 7 December 2025. He was introduced by professor Gunilla Karlsson Hedestam, member of the Nobel Assembly at Karolinska Institutet.