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Scientific background Discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19 When SARS-CoV-2 emerged in late 2019 and rapidly spread to all parts of the world, few thought that vaccines could be developed in time to help curb the increasing global disease burden. Yet, several vaccines were approved in…

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Scientific background Discoveries concerning the genomes of extinct hominins and human evolution The 2022 Nobel Prize in Physiology or Medicine is awarded to Svante Pääbo for his discoveries concerning the genomes of extinct hominins and human evolution. The relationship between Homo sapiens and extinct hominins has long been a topic of great interest. Paleontology and archeology are…

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Scientific background Discoveries of receptors for temperature and touch The 2021 Nobel Prize in Physiology or Medicine is awarded to David Julius and Ardem Patapoutian for their discoveries of thermal and mechanical transducers. The question of how we sense the physical world through somatic sensation has fascinated humankind for millennia. During the first half of…

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