Physiology or Medicine

The Nobel Prize in Physiology or Medicine 2007   Scientific Advisors, Professors at Karolinska Institutet: Christer Betsholtz, Physiological Chemistry. Bertil Fredholm, Pharmacology, Chair of the Nobel Committee. Göran K. Hansson, Medicine. Hans Jörnvall, Physiological Chemistry, Secretary of the Nobel Assembly. Nils-Göran Larsson, Genetics. Illustrations and layout: Annika Röhl, Bengt Gullbing Copyright © The Nobel Committee…

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The Nobel Prize in Physiology or Medicine 2007 The process of gene targeting involves two steps. Capecchi and Smithies discovered that homologous recombination could be used to specifically modify genes in mammalian cells. Evans identified and isolated embryonic stem cells (ES cells) from early mouse embryos (blastocysts). He also showed that ES cells can be…

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The Nobel Prize in Physiology or Medicine 2007 The consequences of a gene knockout tell us about the function of that gene. Conditional changes, which can be activated at specific time points or in selected tissues, help in establishing the gene’s function at a specific age, or in specific cell types. It is also possible…

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Interview

“I like to see things that have never been seen before” Here, Richard Roberts is interviewed about everything from his love of discovery to his biggest influences – and reveals a determined, curiosity-driven character. The subject of ageing also came up, which is rather fitting since Roberts joined the Nobel Prize Dialogue Seoul to discuss…

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