Bruce Merrifield

Facts

Robert Bruce Merrifield

Photo from the Nobel Foundation archive.

Robert Bruce Merrifield
The Nobel Prize in Chemistry 1984

Born: 15 July 1921, Fort Worth, TX, USA

Died: 14 May 2006, Cresskill, NJ, USA

Affiliation at the time of the award: Rockefeller University, New York, NY, USA

Prize motivation: "for his development of methodology for chemical synthesis on a solid matrix."

Prize share: 1/1

Work

Peptides and proteins are substance of fundamental importance for all life. These molecules consist of amino acids assembled in chains and can be produced by artificial means by building the chain in steps. At the beginning of the 1960s, Bruce Merrifield developed a method for avoiding significant impurities in the final product that result from a relatively small amount of impurities in each step. If a chain-formed molecule in solid form is attached to the first amino acid, impurities can be rinsed away between every step. This process can be carried out mechanically.

To cite this section
MLA style: Bruce Merrifield – Facts. NobelPrize.org. Nobel Media AB 2018. Fri. 16 Nov 2018. <https://www.nobelprize.org/prizes/chemistry/1984/merrifield/facts/>

Back to top Back To Top Takes users back to the top of the page

Explore prizes and laureates

Look for popular awards and laureates in different fields, and discover the history of the Nobel Prize.