Donald J. Cram
Born: 22 April 1919, Chester, VT, USA
Died: 17 June 2001, Palm Desert, CA, USA
Affiliation at the time of the award: University of California, Los Angeles, CA, USA
Prize motivation: "for their development and use of molecules with structure-specific interactions of high selectivity."
Prize share: 1/3
Chemical reactions often occur through the influence of molecules that have cavities and pockets where other atoms and molecules can be attached to then join with other molecules. After Charles Pedersen discovered crown ethers, molecules that can capture certain metallic atoms, Donald Cram succeeded in building molecules with the ability to attach specific atoms and molecules to themselves. This made it possible to create chemical compounds through chemical reactions that have a significant impact on biological processes.