John R. Vane

Facts

John R. Vane

Photo from the Nobel Foundation archive.

John R. Vane

Born: 29 March 1927, Tardebigg, United Kingdom

Died: 19 November 2004, Farnborough, United Kingdom

Affiliation at the time of the award: The Wellcome Research Laboratories, Beckenham, United Kingdom

Prize motivation: "for their discoveries concerning prostaglandins and related biologically active substances."

Prize share: 1/3

Work

Prostaglandins are hormone-like substances that govern several important processes in the body. They also come into play when the body is under attack. In 1971 John Vane showed that acetylsalicylic acid, a substance found in pain-relieving and fever-reducing medications like aspirin, works by inhibiting the formation of prostglandins. In 1976 he discovered the prostacyclin prostglandin, which expands the smallest blood vessels and, unlike certain other prostglandins, inhibits the formation of blood particles called platelets that cause blood to coagulate.

To cite this section
MLA style: John R. Vane – Facts. NobelPrize.org. Nobel Media AB 2018. Tue. 13 Nov 2018. <https://www.nobelprize.org/prizes/medicine/1982/vane/facts/>

Back to top Back To Top Takes users back to the top of the page

Explore prizes and laureates

Look for popular awards and laureates in different fields, and discover the history of the Nobel Prize.