Physiology or Medicine

Today many important protein drugs (e.g. growth hormone, erythropoetin, insulin) are produced in living cells. To facilitate easy purification, the proteins are provided with a signal peptide causing them to be secreted out of the cell. For scale-up production, cells are grown in bioreactors.

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How do newly synthesized proteins find their correct destinations within a cell, and how are they able to pass across the tightly sealed intracellular membranes? These were the central questions that Günter Blobel began to address in the late 1960s. He started by analyzing how newly synthesized secretory proteins are first targeted to and then…

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Award ceremony speech

Swedish Presentationstal av Professor Christer Höög, ledamot av , 10 December 2010 Professor Christer Höög presenterar Nobelpriset i fysiologi eller medicin 2010 i Stockholms Konserthus. Eders Majestäter, Eders Kungliga Högheter, mina Damer och Herrar, Årets Nobelpris i Fysiologi eller Medicin belönar en av vår tids stora medicinska landvinningar, in vitro-fertilisering – också kallad…

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Press release

Swedish 2010-10-04 har idag beslutat att Nobelpriset i Fysiologi eller Medicin år 2010 tilldelas Robert G. Edwards för utvecklingen av in vitro-fertilisering Sammanfattning Robert Edwards belönas med 2010 års Nobelpris för utvecklingen av in vitro-fertilisering (IVF eller provrörsbefruktning). Hans insatser har gjort det möjligt att behandla ofrivillig barnlöshet (infertilitet), ett problem som mer än 10…

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  The Nobel Assembly at the Karolinska Institute in Stockholm, Sweden, has awarded the Nobel Prize in Physiology or Medicine for 1995 to Edward B. Lewis, Christiane Nüsslein-Volhard and Eric Wieschaus for their discoveries concerning “the genetic control of early embryonic development”.   From Egg to Adult Fly   The adult fly consists of head,…

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Other resources

A chromosome having the standard sequence of regions labelled 1 to 7, inclusive, is shown on the left. If a segment labelled 2 and 3 becomes inverted then the new configuration shown on the right is called an inversion. When the standard and inverted chromosomes pair with one another the result is a chromosome loop…

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