Hans Adolf Krebs
The Nobel Prize in Physiology or Medicine 1953
Born: 25 August 1900, Hildesheim, Germany
Died: 22 November 1981, Oxford, United Kingdom
Affiliation at the time of the award: Sheffield University, Sheffield, United Kingdom
Prize motivation: "for his discovery of the citric acid cycle."
Prize share: 1/2
Nutrients are broken down in our cells to release energy for the construction of cells. After Albert Szent-Györgyi identified several important reactions in these metabolic processes, in 1937 Hans Krebs was able to present a complete picture of an important part of metabolism - the citric acid cycle. In this process, which is cyclical and has several steps, nutrients are converted to other molecules with a large amount of chemical energy. The latter are ultimately converted into adenosine triphosphate (ATP), which provides chemical energy to facilitate other biochemical processes in the cell.
Their work and discoveries range from cancer therapy and laser physics to developing proteins that can solve humankind’s chemical problems. The work of the 2018 Nobel Laureates also included combating war crimes, as well as integrating innovation and climate with economic growth. Find out more.